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SML1998

Sigma-Aldrich

KLH45

≥98% (HPLC)

Synonym(s):

N-Cyclohexyl-N-phenethyl-4-(4-(trifluoromethoxy)phenyl)-2H-1,2,3-triazole-2-carboxamide

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5 MG
$103.00
25 MG
$332.00

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Available to ship onApril 29, 2025Details

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5 MG
$103.00
25 MG
$332.00

About This Item

Empirical Formula (Hill Notation):
C24H25F3N4O2
CAS Number:
1632236-44-2
Molecular Weight:
458.48
MDL number:
MFCD30742935
UNSPSC Code:
12352200
NACRES:
NA.77

$103.00

Available to ship onApril 29, 2025Details

Request a Bulk Order

assay

≥98% (HPLC)

form

oil

color

colorless to light yellow

storage temp.

2-8°C

SMILES string

O=C(N(CCC1=CC=CC=C1)C2CCCCC2)N(N=C3)N=C3C4=CC=C(OC(F)(F)F)C=C4

InChI

1S/C24H25F3N4O2/c25-24(26,27)33-21-13-11-19(12-14-21)22-17-28-31(29-22)23(32)30(20-9-5-2-6-10-20)16-15-18-7-3-1-4-8-18/h1,3-4,7-8,11-14,17,20H,2,5-6,9-10,15-16H2

InChI key

FYOYNRLSBYWAHL-UHFFFAOYSA-N

Biochem/physiol Actions

In vivo-active, potent and selective irreversible inhibitor of DDHD2
KLH45 is an in vivo-active, potent and selective irreversible inhibitor of DDHD2. KLH45 inactivates brain levels of DDHD2 and increases levels of triglycerides in mouse brain.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000419706
0000419706
0000155506
0000155506

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Jordon M Inloes et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(41), 14924-14929 (2014-10-01)
Complex hereditary spastic paraplegia (HSP) is a genetic disorder that causes lower limb spasticity and weakness and intellectual disability. Deleterious mutations in the poorly characterized serine hydrolase DDHD2 are a causative basis for recessive complex HSP. DDHD2 exhibits phospholipase activity

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