SML0643

M617 trifluoroacetate salt

≥95% (HPLC)

• Synonym(s): Galanin(1-13)-Gln14-bradykinin(2-9)amide trifluoroacetate salt
• Empirical Formula (Hill Notation): C₁₁₂H₁₆₁N₂₉O₂₈ · xC₂HF₃O₂
• CAS Number: 860790-38-1
• Molecular Weight: 2361.65 (free base basis)
• UNSPSC Code: 12352202

Properties

• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C112H161N29O28/c1-59(2)44-73(130-97(155)74(45-60(3)4)131-99(157)77(49-66-33-35-68(145)36-34-66)127-90(149)54-121-95(153)62(7)124-104(162)81(57-142)135-102(160)80(51-88(115)147)132-98(156)75(46-61(5)6)134-108(166)93(63(8)144)137-103(161)79(125-89(148)52-113)50-67-53-120-70-27-16-15-26-69(67)70)96(154)123-56-92(151)138-40-18-30-84(138)106(164)129-72(37-38-87(114)146)109(167)141-43-21-32-86(141)111(169)140-42-19-29-83(140)105(163)122-55-91(150)126-76(47-64-22-11-9-12-23-64)100(158)136-82(58-143)110(168)139-41-20-31-85(139)107(165)133-78(48-65-24-13-10-14-25-65)101(159)128-71(94(116)152)28-17-39-119-112(117)118/h9-16,22-27,33-36,53,59-63,71-86,93,120,142-145H,17-21,28-32,37-52,54-58,113H2,1-8H3,(H2,114,146)(H2,115,147)(H2,116,152)(H,121,153)(H,122,163)(H,123,154)(H,124,162)(H,125,148)(H,126,150)(H,127,149)(H,128,159)(H,129,164)(H,130,155)(H,131,157)(H,132,156)(H,133,165)(H,134,166)(H,135,160)(H,136,158)(H,137,161)(H4,117,118,119)/t62-,63+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,93-/m0/s1
• Inchi Key: PAYBRARNTYCYOT-OTTBQUPZSA-N

Description

Amino Acid Sequence

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2 trifluoroacetate salt

Biochem/physiol Actions

M617, galanin(1–13)-Gln14-bradykinin(2–9)amide, is a chimeric peptide that acts as a selective agonist for the Galanin GalR1 receptor. M617 shows 25-fold specificity for GalR1with Ki values of 0.23 for GAL1 and 5.71 nM for GAL2.

M617is a Galanin GalR1 selective agonist.

Features and Benefits

This compound is featured on the Galanin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable