β-Galactosidase is coded by the LacZ gene, which helps to transform lactose into galactose. β-Galactosidases are used to produce galactooligosaccharides (GOS). Lactobacillus β-galactosidases are heterodimeric proteins, that are coded by lacL and lacM genes.
β-galactosidase is a tetramer made up of identical four polypeptide chains with a molecular weight of 135,000 each and constituting 1023 amino acids. It is very specific for D-galactose and requires K+ or Na+ and Mg2+ to be fully active. It cleaves lactose into its monosaccharide components, glucose and galactose. The sulfhydryl containing enzyme also catalyzes the transglycosylation of glucose into allolactose, the inducer of β-galactosidase, in a feedback loop.
Immunogen
beta-gal antibody was raised against a 17 amino acid peptide from near the amino terminus of E. coliβ-gal.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3500043.
Physical form
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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