SAB2702177

Anti-XPC antibody produced in rabbit

• Synonym(s): RAD4, XP3, XPCC
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human
• concentration: 0.5 mg/mL
• technique(s): western blot: 1:500-1:1000
• UniProt accession no.: Q01831
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... XPC(7508)

Description

General description

XPC (xeroderma pigmentosum group C) is mapped to human chromosome 3p25.1. It has 18 exons and codes for a constituent of the nucleotide excision repair (NER).

Immunogen

Peptide conjugated to a carrier protein

Application

For WB: Load 40ug cell lysate/lane. Use at a dilution of 1:500-1:1000. Optimal dilutions/concentratons should be determined by the researcher.

Biochem/physiol Actions

Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair.
XPC (xeroderma pigmentosum group C) participates in repair reaction. XPC protein defends against cancer. XPC plays a major role in the early stages of global genome nucleotide excision repair (NER).

Features and Benefits

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Physical form

Phosphate-buffered saline, pH 7.2, containing no preservatives

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable