XPC
xeroderma pigmentosum, complementation group C
Synonyms:
RAD4, XP3, XPCC
Species:
Human XPC (7508), Mouse Xpc (22591), Rat Xpc (312560), chicken XPC (416039), Zebrafish xpc (541386), sheep XPC (101109650), domestic cat XPC (101080440), Horse XPC (100050424), dog XPC (476521), naked mole-rat Xpc (101707002) ...More
UniProtKB ID:
Gene ID:
- Human(7508) Summary: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(22591) xeroderma pigmentosum, complementation group C
- Rat(312560) xeroderma pigmentosum, complementation group C
- chicken(416039) xeroderma pigmentosum, complementation group C
- Zebrafish(541386) xeroderma pigmentosum, complementation group C
- sheep(101109650) xeroderma pigmentosum, complementation group C
- domestic cat(101080440) xeroderma pigmentosum, complementation group C
- Horse(100050424) xeroderma pigmentosum, complementation group C
- dog(476521) xeroderma pigmentosum, complementation group C
- naked mole-rat(101707002) xeroderma pigmentosum, complementation group C
- domestic guinea pig(100719007) xeroderma pigmentosum, complementation group C
- Domestic Rabbit(100346279) xeroderma pigmentosum, complementation group C
- cow(524274) xeroderma pigmentosum, complementation group C
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-XPC antibody produced in mouse, ,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-XPC (C-terminal) antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-XPC antibody produced in rabbit, ,
Species Reactivity
human
Application
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot