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S6686

Sigma-Aldrich

Anti-Sodium Channel, Brain Type III antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-BIII, Anti-SCN3A, Anti-SP32III

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

immunohistochemistry (frozen sections): suitable
western blot: 1:200 using newborn rat brain membranes

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

Immunogen

synthetic peptide corresponding to amino acids 511-524 of the α subunit of rat type III voltage-gated sodium channel (VGSC, SP32III) with additional N-terminal lysine and tyrosine. The epitope corresponds to the sequence in the intracellular loop between the I and II domains of type III VGSC α subunit.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% sodium azide.

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M Noda et al.
Nature, 322(6082), 826-828 (1986-08-03)
The voltage-gated sodium channel is a transmembrane protein essential for the generation of action potentials in excitable cells. It has been reported that sodium channels purified from the electric organ of the electric eel, Electrophorus electricus, and from chick cardiac

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