synthetic peptide corresponding to amino acids 511-524 of the α subunit of rat type III voltage-gated sodium channel (VGSC, SP32III) with additional N-terminal lysine and tyrosine. The epitope corresponds to the sequence in the intracellular loop between the I and II domains of type III VGSC α subunit.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% sodium azide.
The voltage-gated sodium channel is a transmembrane protein essential for the generation of action potentials in excitable cells. It has been reported that sodium channels purified from the electric organ of the electric eel, Electrophorus electricus, and from chick cardiac
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