Preeclampsia is a complication of pregnancy characterised by gestational hypertension, proteinuria and/or end organ disease. The reduced uteroplacental perfusion (RUPP) model, via partial occlusion of the lower abdominal aorta, mimics insufficient placental perfusion as a primary causal characteristic of preeclampsia.
Development (Cambridge, England), 147(11) (2020-05-31)
Although widely used, assisted reproductive technologies (ARTs) are associated with adverse perinatal outcomes. To elucidate their underlying causes, we have conducted a longitudinal analysis of placental development and fetal growth using a mouse model to investigate the effects of individual
ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia.
Patricia Villie et al.
American journal of obstetrics and gynecology, 220(3), 284-285 (2018-12-24)
Current medical science, 40(4), 671-676 (2020-08-31)
Acute respiratory distress syndrome (ARDS) is associated with a mortality of 45%. Our previous research indicated that anti-vascular endothelial growth factor (VEGF) could maintain the normal structure and function of the respiratory barrier. However, systemic application of VEGF antagonists would
American journal of physiology. Regulatory, integrative and comparative physiology, 318(6), R1047-R1057 (2020-05-07)
Preeclampsia is a spontaneously occurring, pregnancy-specific syndrome that is clinically diagnosed by new onset hypertension and proteinuria. Epidemiological evidence describes an association between a history of preeclampsia and increased risk for cardiovascular disease in later life; however, the mechanism(s) driving
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