P5164
Anti-Prostaglandin E2 antibody produced in rabbit
whole antiserum, lyophilized powder
Synonym(s):
PGE2 Antibody - Anti-Prostaglandin E2 antibody produced in rabbit, Pge2 Antibody
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About This Item
MDL number:
UNSPSC Code:
12352203
Recommended Products
biological source
rabbit
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
contains
0.02% sodium azide
technique(s)
radioimmunoassay: suitable
storage temp.
2-8°C
General description
PGE2, a member of the prostaglandin family, is a bioactive lipid molecule produced by cyclooxygenase. Its increased endometrial biosynthesis induces labor and dysmenorrhea. In cardiovascular and immune systems, it enhances the inflammation triggered by leukotrienes. PGE2 can inhibit the release of mediators, as well as regulate monocyte-macrophages and dendritic cells. Anti-Prostaglandin E2 antibody can be used to quantify PGE by radioimmunoassay. Rabbit anti-Prostaglandin E2 antibody reacts with PGE2 and PGE1.
Immunogen
PGE2-BSA
Application
Anti-Prostaglandin E2 antibody (diluted 1:300) can be used in direct EIA (enzyme immunoassay) to determine the concentration of PG.
Reconstitution
Reconstitute with 5 mL 0.01M phosphate buffered saline, pH 7.4, containing 0.1% bovine serum albumin and 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
13 - Non Combustible Solids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Silvana R Ferreira et al.
Reproduction, fertility, and development (2019-05-02)
It is known that androgen excess induces changes in fetal programming that affect several physiological pathways. Peroxisome proliferator-activated receptors (PPARs) α, δ and γ are key mediators of female reproductive functions, in particular in uterine tissues. Thus, we aimed to
Izabela Woclawek-Potocka et al.
Reproduction (Cambridge, England), 137(1), 95-105 (2008-10-03)
Lysophosphatidic acid (LPA) modulates prostaglandin (PG) synthesis via LPA receptor 3 (LPAR3) in the murine endometrium. The lack of functional LPAR3 in mice may lead to embryo mortality. In the present study, we examined the role of LPA in the
Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics.
Charles N Serhan et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(15), 8609-8611 (2003-07-16)
Agnieszka Blitek et al.
The Journal of reproduction and development, 56(6), 643-648 (2010-09-04)
The homeobox A (HOXA) family of genes is responsible for segmental development of the female reproductive tract during embryogenesis. However, HOXA10 has been shown to be essential not only for uterus development, but also for implantation. Persistent expression and steroid-dependent
M J Siemieniuch et al.
Polish journal of veterinary sciences, 13(4), 605-613 (2010-01-01)
Tumor Necrosis Factor-alpha (TNFalpha) is a pleiotrophic cytokine, affects either normal or tumor cells, and influences cellular differentiation. TNFalpha role in female reproduction has been proven to be mediated through an influence on prostaglandin (PGs) synthesis and output. To evaluate
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