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Key Documents

P0887

Sigma-Aldrich

Polydeoxyadenylic acid sodium salt

Synonym(s):

Poly(dA)

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
41106305
NACRES:
NA.51

biological source

synthetic (organic)

form

powder

storage temp.

−20°C

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Application

Polydeoxyadenylic acid (Poly(dA)) may be used in physicochemical studies on small molecule binding and interaction and self-assembly dynamics that affect its biological functions.

Unit Definition

One unit will yield an A260 of 1.0 in 1.0 ml of water (1 cm light path).

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Eduardo Gorab et al.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 17(6), 821-832 (2009-09-19)
Antibodies to specific nucleic acid conformations are amongst the methods that have allowed the study of non-canonical (Watson-Crick) DNA structures in higher organisms. In this work, the structural limitations for the immunological detection of DNA.RNA hybrid duplexes were examined using
Sooyeon Kim et al.
The journal of physical chemistry. B, 115(51), 15399-15405 (2011-11-17)
The investigation on the self-assembly of polydeoxyadenylic acid (poly(dA)) is highly important to fully understand its biological function and for its application in the field of nanotechnology. Using the fluorescence resonance energy transfer (FRET) technique, we report investigations for the
Yusuke Sanada et al.
The journal of physical chemistry. B, 116(1), 87-94 (2011-11-18)
A certain length of poly(deoxyadenylic acid) (dA(X)) can form a novel complex with β-1,3-D-glucan schizophyllan (SPG) with a stoichiometric composition of one dA binding two main chain glucoses. We measured dilute solution properties for the complex with light and small-angle
Paul D Dinkel et al.
Biochemistry, 54(30), 4731-4740 (2015-07-16)
Tau fibrils are the main proteinacious components of neurofibrillary lesions in Alzheimer disease. Although RNA molecules are sequestered into these lesions, their relationship to Tau fibrils is only poorly understood. Such understanding, however, is important, as short fibrils can transfer

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