MAK024

Cobalt Assay

sufficient for 100 colorimetric tests

• Synonym(s): Cobalt Quantitation Kit
• UNSPSC Code: 12352200
• NACRES: NA.84

Properties

• usage: sufficient for 100 colorimetric tests
• application(s): cosmetics; food and beverages
• detection method: colorimetric
• storage temp.: room temp

Description

General description

Cobalt is a transition metal that serves as a trace dietary mineral for all multicellular organisms. Cobalt is an important cofactor for the Vitamin B₁₂ class of compounds where it occupies the center of the vitamin B₁₂ corrin ring.[1] Cobalt can also be coordinated in the active site of the non-corrin containing metalloenzyme methionine aminopeptidase.[1]

Suitability

Suitable for quantitating cobalt concentrations in a variety of samples

Principle

The Cobalt Assay kit provides a simple and direct procedure for measuring cobalt in a variety of samples. In this assay, cobalt reacts with 2-mercaptoethanol under basic conditions to form a complex with a strong absorbance at 475 nm. Interference from the metal ions Fe²⁺, Cu²⁺, Ni²⁺, Zn²⁺, and Mn²⁺ is <10% at this wavelength. This assay gives a linear range of 10-50 nmoles of cobalt.

Safety Information

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H302,H310,H315,H317,H318,H331,H334,H341,H350,H360FD,H373,H410
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
• target_organs: Liver,Heart
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials