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M6756

Sigma-Aldrich

Microperoxidase (MP-11) sodium salt

≥85% (HPLC)

Synonym(s):

Microperoxidase-11, heme undecapeptide of cytochrome c

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About This Item

Empirical Formula (Hill Notation):
C84H116FeN20O21S2
CAS Number:
Molecular Weight:
1861.92
UNSPSC Code:
12352204
NACRES:
NA.54

assay

≥85% (HPLC)

form

powder

storage temp.

−20°C

Application

Microperoxidase (MP-11) has been used in a study to assess its electrochemistry by cyclic voltammetry with multi-walled carbon nanotubes (MWNTs). It has also been used in a study as a label to investigate electrochemical immunosensing.

Biochem/physiol Actions

The oxidation of methyl phenyl sulfide to methyl phenyl sulfoxide by Microperoxidase-11 was promoted by low concentrations of alcohol but inhibited by high levels in the solvent.

Other Notes

The proposed structure is the heme portion of the cytochrome c molecule with amino acids 11-21 still attached.

Preparation Note

Prepared by enzymatic degradation of equine heart cytochrome c.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K D Vandegriff et al.
British journal of pharmacology, 154(8), 1649-1661 (2008-06-10)
MP4 (Hemospan) is a Hb-based oxygen therapeutic agent, based on polyethylene-glycol (PEG) conjugation to Hb, undergoing clinical trials as an oxygen carrier. This study describes the functional interaction between MP4 and carbon monoxide (CO), as a CO delivery agent, and
J G Ma et al.
Biochemistry, 38(9), 2787-2795 (1999-03-03)
Resonance Raman and UV-visible absorption spectra show that nickel(II) microperoxidase-11 (NiMP-11) is four-coordinate in aqueous solution in the pH range from 1.0 to 13.0. In aqueous solutions of NiMP-11 in the absence of cetyltrimethylammonium bromide (CTAB), NiMP-11 is aggregated. In
The effect of solvent on the catalytic properties of microperoxidase-11.
O'Reilly, N.
Physiological Chemistry and Physics, 13, 5304-5313 (2011)
Direct electrochemistry of microperoxidase11 using carbon nanotube modified electrodes
Wang, M., et al.
Journal of Electroanalytical Chemistry (Lausanne Switzerland), 578, 121-127 (2005)
A heme-peptide as an ultrastructural tracer.
N Feder
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 18(12), 911-913 (1970-12-01)

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