Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 112(1), 61-67 (1995-09-01)
Carbachol treatment in Bufo arenarum oocytes decreases the radioactivity in [32P]PIP2 in the following 20 min after stimulation and increases the [3H]glycerol labeling of 1,2-DAG at 1 min of stimulation. On the contrary, in Dieldrin treated oocytes carbachol stimulation produces
Inositol 1,4,5-trisphosphate (IP3) has long been recognized as a second messenger for intracellular Ca2+ mobilization. Recently, sphingosine 1-phosphate (S1P) has been shown to be involved in Ca2+ release from the endoplasmic reticulum (ER). Here, we investigated the role of S1P
Inositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate, administered exogenously at a concentration of 3 x 10(-5) mol/l increased LH release in superfused rat pituitary cells by 950 +/- 267% and 281 +/- 83%, respectively. This stimulatory effect was reversible and dose-dependent. Other
Regulation of intracellular calcium homeostasis by means of secondary mediators calmodulin and 4,5-inositol phosphates (products of phosphatidyl inositol hydrolysis) was studied in children with ectopic forms of arrhythmias. Alterations in the system calmodulin-Ca2+ and the activity of phosphoinosite metabolism correlated
The Journal of biological chemistry, 273(6), 3791-3797 (1998-03-07)
Hydrolysis of GTP by dynamin is essential for budding clathrin-coated vesicles from the plasma membrane. Two distinct domains of dynamin are implicated in the interactions with dynamin GTPase activators. Microtubules and Grb2 bind to the carboxyl-terminal proline/arginine-rich domain (PRD), whereas
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