C9650
β-Cyano-L-alanine
≥95%, suitable for ligand binding assays
Synonym(s):
3-cyano-L-alanine
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250 MG
$628.00
About This Item
Empirical Formula (Hill Notation):
C4H6N2O2
CAS Number:
Molecular Weight:
114.10
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
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Product Name
β-Cyano-L-alanine, ≥95%
Quality Level
assay
≥95%
form
powder
technique(s)
ligand binding assay: suitable
color
white
mp
217 °C
storage temp.
−20°C
SMILES string
OC([C@@H](N)CC#N)=O
InChI
1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1
InChI key
BXRLWGXPSRYJDZ-VKHMYHEASA-N
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Biochem/physiol Actions
β-Cyano-L-alanine (BCA) is used as a cystathione γ-lyase (CSE) inhibitor to study the physiological roles of hydrogen sulfide in processes such as angiogenesis and hypertension.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Andrew J M Howden et al.
The Plant journal : for cell and molecular biology, 57(2), 243-253 (2008-09-13)
Pseudomonas fluorescens SBW25 is a plant growth-promoting bacterium that efficiently colonizes the leaf surfaces and rhizosphere of a range of plants. Previous studies have identified a putative plant-induced nitrilase gene (pinA) in P. fluorescens SBW25 that is expressed in the
M Piotrowski et al.
The Journal of biological chemistry, 276(4), 2616-2621 (2000-11-04)
Nitrilases (nitrile aminohydrolases, EC ) are enzymes that catalyze the hydrolysis of nitriles to the corresponding carbon acids. Among the four known nitrilases of Arabidopsis thaliana, the isoform NIT4 is the most divergent one, and homologs of NIT4 are also
Ting-Ting Pan et al.
Journal of molecular and cellular cardiology, 40(1), 119-130 (2005-12-06)
The possible role of hydrogen sulfide (H2S) in cardioprotection was investigated in isolated rat ventricular myocytes exposed to severe metabolic inhibition (MI) in glucose-free buffer containing 2-deoxy-D-glucose (2-DOG), an inhibitor of glycolysis. Pretreatment (30 min) with NaHS (a H2S donor)
Liping Fang et al.
Journal of hypertension, 27(11), 2174-2185 (2009-08-01)
Recently, periadventitial adipose tissue (PAT) was found to secrete bioactive factors playing an important role in the regulation of vascular tension. Hydrogen sulfide (H(2)S), a novel cardiovascular gasotransmitter, relaxes vessels through the K(ATP) channel in a calcium-dependent and endothelial-independent manner.
B Teague et al.
British journal of pharmacology, 137(2), 139-145 (2002-09-05)
1. Sodium hydrogen sulphide (NaHS), a donor of hydrogen sulphide (H(2)S), produced dose-related relaxation of the rabbit isolated ileum (EC(50), 76.4+/-7.9 microM) and rat vas deferens (EC(50), 64.8+/-5.4 microM) and reduced ACh-mediated contraction of the guinea-pig isolated ileum. 2. NaHS
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