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C8984

Sigma-Aldrich

Z-Leu-Leu-Leu-fluoromethyl ketone

≥90% (TLC)

Synonym(s):

Z-LLL-FMK

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About This Item

Empirical Formula (Hill Notation):
C27H42N3O5F
Molecular Weight:
507.64
MDL number:
MFCD03453603
UNSPSC Code:
12352200
PubChem Substance ID:
329775191
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

assay

≥90% (TLC)

form

powder

solubility

acetone: 10 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)CF

InChI

1S/C27H42FN3O5/c1-17(2)12-21(24(32)15-28)29-25(33)22(13-18(3)4)30-26(34)23(14-19(5)6)31-27(35)36-16-20-10-8-7-9-11-20/h7-11,17-19,21-23H,12-16H2,1-6H3,(H,29,33)(H,30,34)(H,31,35)/t21-,22-,23-/m0/s1

InChI key

HLXJVMRDGBCZCM-VABKMULXSA-N

Amino Acid Sequence

Z-Leu-Leu-Leu-FMK

Biochem/physiol Actions

Z-Leu-Leu-Leu-fluoromethyl ketone is a proteosome inhibitor.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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