C8984
Z-Leu-Leu-Leu-fluoromethyl ketone
≥90% (TLC)
Synonym(s):
Z-LLL-FMK
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About This Item
Empirical Formula (Hill Notation):
C27H42N3O5F
Molecular Weight:
507.64
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
biological source
synthetic (organic)
Quality Level
assay
≥90% (TLC)
form
powder
solubility
acetone: 10 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)CF
InChI
1S/C27H42FN3O5/c1-17(2)12-21(24(32)15-28)29-25(33)22(13-18(3)4)30-26(34)23(14-19(5)6)31-27(35)36-16-20-10-8-7-9-11-20/h7-11,17-19,21-23H,12-16H2,1-6H3,(H,29,33)(H,30,34)(H,31,35)/t21-,22-,23-/m0/s1
InChI key
HLXJVMRDGBCZCM-VABKMULXSA-N
Biochem/physiol Actions
Z-Leu-Leu-Leu-fluoromethyl ketone is a proteosome inhibitor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Tianling Ou et al.
PLoS pathogens, 17(1), e1009212-e1009212 (2021-01-20)
Hydroxychloroquine, used to treat malaria and some autoimmune disorders, potently inhibits viral infection of SARS coronavirus (SARS-CoV-1) and SARS-CoV-2 in cell-culture studies. However, human clinical trials of hydroxychloroquine failed to establish its usefulness as treatment for COVID-19. This compound is
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C8984-3MG | 04061833261224 |