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C0856

Sigma-Aldrich

C7BzO

Synonym(s):

3-(4-Heptyl)phenyl-3-hydroxypropyl)dimethylammoniopropanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C21H37NO4S
Molecular Weight:
399.59
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.56

$155.70

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Available to ship onMay 01, 2025Details


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description

zwitterionic

assay

≥95.0% (HPLC)

form

solid

mol wt

399.59 Da (anhydrous)

aggregation number

≤25

technique(s)

dialysis: suitable
electrophoresis: suitable
protein quantification: suitable

SMILES string

CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3

InChI key

FUPYROAFYPQUSH-UHFFFAOYSA-N

General description

3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility.[1] C7BzO is effective in sample preparation from plant membranes.[2]

Application

C7BzO has been used as a component of extraction solution for protein isolation from mycelia[3] and recombinant mammalian prion proteins.[4]

Other Notes

Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Alaa A Alaswad et al.
International journal of molecular sciences, 20(5) (2019-03-06)
Pigeon pea (Cajanus cajan (L.) Millspaugh) is cultivated widely in semiarid agricultural regions in over 90 countries around the world. This important legume can enter into symbiotic associations with a wide range of rhizobia including Bradyrhizobium and fast-growing rhizobia. In
Improved high-yield expression, purification and refolding of recombinant mammalian prion proteins under aerosol-free elevated biological safety conditions
Rehbein P and Schwalbe H
Protein Expression and Purification, 150, 53-60 (2018)
Structure-efficiency relationships of zwitterionic detergents as protein solubilizers in two-dimensional electrophoresis
Tastet C, et al.
Proteomics, 3(2), 111-121 (2003)
T Rabilloud et al.
Electrophoresis, 20(18), 3603-3610 (1999-12-28)
Parasite-encoded membrane proteins translocated to the surface of infected erythrocytes or in specialized vesicles underneath (Maurer's clefts) play a key role in the asexual life cycle of Plasmodium falciparum (a malaria-causing protozoan), by mediating key steps such as red blood
Yang Yang et al.
Journal of biochemistry and molecular biology, 39(2), 145-149 (2006-04-06)
To analyze the effect of Maltol on the apoptosis of Human Neuroblastoma Cells (SH-SY5Y) treated by free radical which was generated from Hydrogen Peroxide (H2O2), flow cytometry analysis on Phosphatidylserine (PS) inverting percentage was applied to determine the apoptosis. MTT

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