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C0856

Sigma-Aldrich

C7BzO

Synonym(s):

3-(4-Heptyl)phenyl-3-hydroxypropyl)dimethylammoniopropanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C21H37NO4S
Molecular Weight:
399.59
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.56

description

zwitterionic

assay

≥95.0% (HPLC)

form

solid

mol wt

399.59 Da (anhydrous)

aggregation number

≤25

technique(s)

dialysis: suitable
electrophoresis: suitable
protein quantification: suitable

SMILES string

CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3

InChI key

FUPYROAFYPQUSH-UHFFFAOYSA-N

General description

3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility. C7BzO is effective in sample preparation from plant membranes.

application

C7BzO has been used as a component of extraction solution for protein isolation from mycelia and recombinant mammalian prion proteins.

Other Notes

Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Yang Yang et al.
Journal of biochemistry and molecular biology, 39(2), 145-149 (2006-04-06)
To analyze the effect of Maltol on the apoptosis of Human Neuroblastoma Cells (SH-SY5Y) treated by free radical which was generated from Hydrogen Peroxide (H2O2), flow cytometry analysis on Phosphatidylserine (PS) inverting percentage was applied to determine the apoptosis. MTT
Luana Vieira da Silva et al.
Bioprocess and biosystems engineering, 43(9), 1703-1715 (2020-05-05)
Nitrogen-limiting condition is essential for citric acid production by Yarrowia lipolytica. Mitochondrial protein expression profiles of Y. lipolytica IMUFRJ 50,682 cells cultivated in biomass proliferation medium (YPG medium, yeast extract, peptone and glycerol) and citric acid production medium (CA medium)
Evaluation of nonionic and zwitterionic detergents as membrane protein solubilizers in two-dimensional electrophoresis
Luche S, et al.
Proteomics, 3(3), 249-253 (2003)
Hari B Krishnan et al.
Proteomics, 9(11), 3174-3188 (2009-06-16)
2-D analysis of plant proteomes containing thousands of proteins has limited dynamic resolution because only abundant proteins can be detected. Proteomic assessment of the non-abundant proteins within seeds is difficult when 60-80% is storage proteins. Resolution can be improved through
Proteomic response of the biological control fungus Trichoderma atroviride to growth on the cell walls of Rhizoctonia solani
Grinyer J, et al.
Current Genetics, 47(6), 381-388 (2005)

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