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Key Documents

AV49890

Sigma-Aldrich

Anti-BTNL8 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Butyrophilin-like 8, Anti-FLJ21458, Anti-MGC149619

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100 μL
$541.00

$541.00

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100 μL
$541.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$541.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

57 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_001035552

UniProt accession no.

Q6UX41

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BTNL8(79908)

Immunogen

Synthetic peptide directed towards the N terminal region of human BTNL8

Application

Anti-BTNL8 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/ml.

Biochem/physiol Actions

BTNL8 is one of the butyrophilin (BTN)-like molecules that are involved in initiation and regulation of immune responses. BTNL8 augments the antigen-induced activation of T cells and is probably involved in priming of naïve T lymphocytes.

Sequence

Synthetic peptide located within the following region: MALMLSLVLSLLKLGSGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEA

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC21683

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Andrei I Chapoval et al.
Molecular immunology, 56(4), 819-828 (2013-09-17)
The role of the B7 family molecules in the regulation of the immune response is well documented. A large body of experimental evidence indicates that costimulatory molecules such as B7-1, B7-2, B7-DC, B7-H1, B7-H2, B7-H3 and B7-H4 are critical for

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