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A7227

Sigma-Aldrich

Anti-ADAM-13, Cytoplasmic Domain antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-A Disintegrin And Metalloproteinase-13, Anti-X-ADAM-13

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About This Item

MDL number:
MFCD04974656
UNSPSC Code:
12352203

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

Xenopus

concentration

~1 mg/mL

technique(s)

western blot: 1:1,000

shipped in

wet ice

storage temp.

−20°C

Gene Information

Xenopus laevis ... ADAM13(386623)

General description

ADAM 13 belongs to the metalloproteinase family having a disintegrin-like domain (ADAM). ADAM13 may modulate cell-attachment by associating with integrins through cysteine-rich domains. It is also involved in the migration of neural crest-cells.
Rabbit Anti-ADAM-13, Cytoplasmic Domain antibody binds to Xenopus ADAM13.
By immunoblotting against the reduced protein, the antibody identifies bands at 120 kDa (minor band), 92 kDa (major band), and cleaved products at 68 kDa, 40 kDa in cell lysates.

Immunogen

synthetic peptide corresponding to the C-terminus of Xenopus ADAM-13.

Application

Rabbit Anti-ADAM-13, Cytoplasmic Domain antibody can be used for western blot applications at 1:1,000.

Physical form

Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificates of Analysis (COA)

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D Alfandari et al.
Current biology : CB, 11(12), 918-930 (2001-07-13)
Cranial neural-crest (CNC) cells originate from the lateral edge of the anterior neuroepithelium and migrate to form parts of the peripheral nervous system, muscles, cartilage, and bones of the face. Neural crest-cell migration involves the loss of adhesion from the

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