75762
3-Deoxyglucosone
≥75% (TLC)
Synonym(s):
3-Deoxy-D-erythro-hexosulose
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About This Item
Recommended Products
assay
≥75% (TLC)
form
solid
color
faintly yellow to orange
storage temp.
room temp
SMILES string
OC[C@H]1OC(O)C(=O)C[C@@H]1O
InChI
1S/C6H10O5/c7-2-5-3(8)1-4(9)6(10)11-5/h3,5-8,10H,1-2H2/t3-,5+,6?/m0/s1
InChI key
UHPMJDGOAZMIID-OPAZFOKUSA-N
application
3-Deoxyglucosone is used as a reference for the analysis and detection of glucose degradation products, glycating agents, generated by processes such as heat sterilization.
Other Notes
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Stefan Mittelmaier et al.
Analytical chemistry, 83(24), 9660-9668 (2011-11-16)
The use of advanced glycation end-products (AGEs) as biomarkers for diagnosis and clinical studies is still hampered by insufficient knowledge on clinically relevant structures formed from precursors associated with defined disease states. The present study conducted untargeted analysis of the
Caatje Y le Poole et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 32(1), 45-54 (2011-06-03)
Standard peritoneal dialysis (PD) solutions contain high levels of glucose and glucose degradation products (GDPs), both contributing to the formation of advanced glycation end products (AGEs). We studied the contribution to plasma GDP and AGE levels of 2 PD regimens
Alberto Ortiz et al.
Current medicinal chemistry, 13(22), 2695-2702 (2006-10-05)
Breakdown of glucose under physiological conditions gives rise to glucose degradation products (GDPs). GDPs are also formed during heat sterilization of glucose-containing peritoneal dialysis fluids (PD-fluids). In PD-fluids GDPs have been shown in many different in vitro assays to be
3-Deoxy-glucosone is an intermediate in the formation of furfurals from D-glucose.
Harishchandra Jadhav et al.
ChemSusChem, 4(8), 1049-1051 (2011-07-01)
Lian Engelen et al.
European journal of endocrinology, 164(3), 371-379 (2011-01-06)
Metformin has been reported to reduce α-dicarbonyls, which are known to contribute to diabetic complications. It is unclear whether this is due to direct quenching of α-dicarbonyls or to an improvement in glycemic control. We therefore compared the effects of
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