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This glyoxal is not deionized. As mentioned in the DESCRIPTION section under 'Other Notes', the form of glyoxal is composed of 3 moles of glyoxal and 2 moles of water in a relatively stable configuration.
50649
Glyoxal solution
for molecular biology, BioReagent, ~40% in H2O (~8.8 M)
Synonym(s):
Ethanedial, Oxalaldehyde
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25 ML
$86.10
100 ML
$306.00
About This Item
Linear Formula:
OHCCHO
CAS Number:
Molecular Weight:
58.04
Beilstein/REAXYS Number:
1732463
MDL number:
UNSPSC Code:
12352114
PubChem Substance ID:
NACRES:
NA.52
form:
liquid
Recommended Products
grade
for molecular biology
Quality Level
product line
BioReagent
form
liquid
concentration
~40% in H2O (~8.8 M)
impurities
DNases, none detected
RNases, none detected
phosphatases, none detected
proteases, none detected
refractive index
n20/D 1.409
anion traces
chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg
cation traces
Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤300 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
storage temp.
2-8°C
SMILES string
[H]C(=O)C([H])=O
InChI
1S/C2H2O2/c3-1-2-4/h1-2H
InChI key
LEQAOMBKQFMDFZ-UHFFFAOYSA-N
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General description
Glyoxal is a nucleic acid denaturant. It acts as a specific probe for homopurine strands of DNA.
Application
Suitable for
- nucleic acid denaturation
- binding of DNA/RNA to nitrocellulose membrane
Other Notes
This form of glyoxal is composed of 3 moles of glyoxal and 2 moles of water in a relatively stable configuration.
May precipitate on storage; redissolve at 50-60 °C.
Caution
May precipitate on storage; redissolve at 50-60 °C.
Principle
Glyoxal forms stable complex with guanine residues that results in denaturation of nucleic acids.
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Description
Pricing
signalword
Warning
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Hybridization of denatured RNA transferred or dotted nitrocellulose paper.
P S Thomas
Methods in enzymology, 100, 255-266 (1983-01-01)
R N Skopp et al.
Analytical biochemistry, 169(1), 132-137 (1988-02-15)
This paper describes agarose gel electrophoresis and silver staining of denatured RNAs. Glyoxal- or formaldehyde-denatured RNAs are electrophoresed in an agarose gel cast on a plastic support using an inert, low conductivity buffer. Following electrophoresis, the gel is stained with
M Vojtisková et al.
Journal of biomolecular structure & dynamics, 5(2), 283-296 (1987-10-01)
Plasmid pEJ4, which is a derivative of pUC19 containing an insert with 60-bp-long homopurine.homopyrimidine tract from sea urchin P. miliaris histone gene spacer, was studied by chemical probes of the DNA structure osmium tetroxide and glyoxal. The former probe reacts
Catherine Lambert et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 18(1), 59-69 (2012-10-30)
The molecular basis of Alzheimer's disease has not been clearly established, but disruption of brain metal ion homeostasis, particularly copper and zinc, might be closely involved in the pathogenesis of this disease and its characteristic β-amyloid neuropathological features. The use
Yu Wang et al.
Chemical Society reviews, 41(11), 4140-4149 (2012-04-18)
Methylglyoxal (MGO) and glyoxal (GO), known as reactive carbonyl species, can be generated endogenously and exogenously (human body and food system). They are attracting increased attention because of their relationship with diabetes and flavour generation. In this review, their characteristics
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Is this glyoxal deionized?
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