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46069

Sigma-Aldrich

Esterase from horse liver

lyophilized, powder, brown, 0.5-1.0 U/mg

Synonym(s):

HLE

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About This Item

CAS Number:
Enzyme Commission number:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
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form

powder

quality

lyophilized

specific activity

0.5-1.0 U/mg

mol wt

Mr ~70000

color

brown

storage temp.

−20°C

Unit Definition

1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol ethyl butyrate (Cat. No. 19230) per minute at pH 8.0 and 25°C

Other Notes

Sales restrictions may apply
Slightly higher ee′s can often be obtained compared to PLE-catalysis[1][2][3]

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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L. Blanco et al.
Tetrahedron Letters, 29, 1915-1915 (1988)
J.E. Guibe et al.
Tetrahedron Letters, 30, 67-67 (1989)
E. Fouque et al.
Synthesis, 661-661 (1989)
Zhe-Yi Hu et al.
Analytical and bioanalytical chemistry, 405(5), 1695-1704 (2012-12-15)
Dabigatran etexilate (DABE) is an oral prodrug that is rapidly converted by esterases to dabigatran (DAB), a direct inhibitor of thrombin. To elucidate the esterase-mediated metabolic pathway of DABE, a high-performance liquid chromatography/mass spectrometry based metabolite identification and semi-quantitative estimation
Takashi Nishiyama et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 1), 44-51 (2013-01-01)
Bacterial biofilm formation is an extremely widespread phenomenon involving the secretion of a protective exopolysaccharide matrix which helps the bacteria to attach to surfaces and to overcome a variety of stresses in different environments. This matrix may also include proteins

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