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45235

Sigma-Aldrich

Eosin Y disodium salt

suitable for electrophoresis

Synonym(s):

2′,4′,5′,7′-Tetrabromofluorescein disodium salt, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, D&C;Red No. 22, Eosin yellowish

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About This Item

Empirical Formula (Hill Notation):
C20H6Br4Na2O5
CAS Number:
17372-87-1
Molecular Weight:
691.85
Colour Index Number:
45380
Beilstein/REAXYS Number:
3586809
EC Number:
241-409-6
MDL number:
MFCD00005040
UNSPSC Code:
12171500
PubChem Substance ID:
57650265

technique(s)

electrophoresis: suitable

solubility

H2O: 0.1 g/mL, dark red

fluorescence

λex 520 nm; λem 540 nm in H2O

suitability

in accordance for electrophoresis test

SMILES string

[Na+].[Na+].[O-]C(=O)c1ccccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c([O-])c(Br)cc24

InChI

1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2

InChI key

SEACYXSIPDVVMV-UHFFFAOYSA-L

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Other Notes

Reversible staining of peptides and proteins after PAGE, followed by recovery of proteins

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

376.9 °F - Pensky-Martens closed cup

flash_point_c

191.6 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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M E Selsted et al.
Analytical biochemistry, 155(2), 270-274 (1986-06-01)
A method for the rapid staining of polypeptides in low-pH, urea-containing polyacrylamide gels is described. After 30 s of immersion in an alkaline solution of eosin Y, a variety of proteins stained with intensities similar to those seen with Coomassie
Toshihisa Yashiro et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(48), 17212-17217 (2014-11-19)
Males and females are in conflict over genetic transmission in the evolution of parthenogenesis, because it enhances female reproductive output but deprives the males' genetic contribution. For males, any trait that coerces females into sexual reproduction should increase their fitness.
Sarah J Hatsell et al.
Science translational medicine, 7(303), 303ra137-303ra137 (2015-09-04)
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by episodically exuberant heterotopic ossification (HO), whereby skeletal muscle is abnormally converted into misplaced, but histologically normal bone. This HO leads to progressive immobility with catastrophic consequences, including death by
Han Shih et al.
Macromolecular rapid communications, 34(3), 269-273 (2013-02-07)
The utility of visible-light-mediated polymerization in tissue engineering has been limited due to the necessary use of potentially cytotoxic coinitiator and comonomer. Here, we report a visible-light-mediated thiol-ene hydrogelation scheme using eosin-Y as the only photoinitiator. Under visible light exposure
Han Shih et al.
ACS applied materials & interfaces, 5(5), 1673-1680 (2013-02-07)
Interfacial visible light-mediated thiol-ene photoclick reactions were developed for preparing step-growth hydrogels with multilayer structures. The effect of a noncleavage type photoinitiator eosin-Y on visible-light-mediated thiol-ene photopolymerization was first characterized using in situ photorheometry, gel fraction, and equilibrium swelling ratio.
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