Evaluation of novel beta-ribosidase substrates for the differentiation of Gram-negative bacteria[1]
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Supplied by Glycosynth Limited, U.S. Patent No. 7,323,488, European Patent Nos. 1436411 and 1438424, for use only in internal research conducted by the purchaser. No rights under the aforementioned patents are conveyed which permit the resale, transfer, or use for purposes other than research. Rights under the aforementioned patents, for purposes other than internal research, may be obtained by contacting Glycosynth Limited.
Journal of applied microbiology, 96(1), 170-176 (2003-12-18)
To synthesize novel substrates for the detection of beta-ribosidase and assess their potential for the differentiation of Gram-negative bacteria. Two novel chromogenic substrates, 3',4'-dihydroxyflavone-4'-beta-D-ribofuranoside (DHF-riboside) and 5-bromo-4-chloro-3-indolyl-beta-D-ribofuranoside (X-riboside) were evaluated along with a known fluorogenic substrate, 4-methylumbelliferyl-beta-D-ribofuranoside (4MU-riboside). A total
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