00020590

1,8-Cineole

primary reference standard

• Synonym(s): Eucalyptol, 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane, 1,8-Cineole, 1,8-Epoxy-p-menthane
• Empirical Formula (Hill Notation): C₁₀H₁₈O
• CAS Number: 470-82-6
• Molecular Weight: 154.25
• Beilstein/REAXYS Number: 105109
• EC Number: 207-431-5
• MDL number: MFCD00167977
• UNSPSC Code: 85151701
• PubChem Substance ID: 329746991
• NACRES: NA.24

Properties

• grade: primary reference standard
• form: liquid
• CofA: certificate is enclosed in each package
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: HWI
• refractive index: n20/D 1.457 (lit.)
• bp: 176-177 °C (lit.)
• mp: 1-2 °C (lit.)
• density: 0.921 g/mL at 25 °C (lit.)
• storage temp.: −20°C
• SMILES string: C[C@]12CC[C@H](CC1)C(C)(C)O2
• InChI: 1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+
• InChI key: WEEGYLXZBRQIMU-WAAGHKOSSA-N

Description

General description

1,8-Cineole is the main constituent of essential oils. It is a terpene oxide. It is used as percutaneous penetration enhancer, skin stimulant in skin baths, treating bronchitis, sinusitis and rheumatism. It has decongestant and antitussive property.

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

1,8-Cineole may have been used in quantitative analysis of volatile and semi-volatile compounds of Salvia officinalis using GC-MS method.

Reference Standard in the analysis of herbal medicinal products

Other Notes

This compound is commonly found in plants of the genus: achillea angelica cinnamomum curcuma eucalyptus mentha salvia thymus valeriana zingiber

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H317
• pcodes: P210 - P233 - P240 - P241 - P280 - P303 + P361 + P353
• Hazard Classifications: Flam. Liq. 3 - Skin Sens. 1
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 125.6 °F - closed cup
• flash_point_c: 52 °C - closed cup