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M2392

Meprobamate

analytical standard

Synonym(s):

2-Methyl-2-propylpropane-1,3-diol dicarbamate, MPB

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About This Item

Empirical Formula (Hill Notation):
C9H18N2O4
CAS Number:
57-53-4
Molecular Weight:
218.25
NACRES:
NA.24
PubChem Substance ID:
329817940
UNSPSC Code:
41116107
EC Number:
200-337-5
MDL number:
MFCD00063428

Key Documents

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grade

analytical standard

Quality Level

200

drug control

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CCCC(C)(COC(N)=O)COC(N)=O

InChI

1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13)

InChI key

NPPQSCRMBWNHMW-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

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45368

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Meprobamate certified reference material, pharmaceutical secondary standard

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PHR8851

Meprobamate

Metronidazole-13C2,15N2 VETRANAL®, analytical standard

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32744

Metronidazole-13C2,15N2

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

format

neat

format

-

format

neat

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

100

grade

analytical standard

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

drug control

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

drug control

-

drug control

-

drug control

-

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

application(s)

pharmaceutical

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Enhances GABAA receptor activity by increasing Cl− currents. At high concentrations, blocks NMDA glutamate receptor currents.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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Fabien Bévalot et al.
International journal of legal medicine, 125(3), 463-468 (2011-02-22)
The use of vitreous humor (VH) as an alternative matrix to blood in the field of forensic toxicology has been described for numerous drugs. Interpretation of drug concentrations measured in VH, as in other matrices, requires statistical analysis of a
Shane A Snyder et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 61(1), 145-154 (2010-01-09)
The presence of pharmaceuticals and endocrine disrupting compounds (EDCs) in the environment raises many questions about risk to the environment and risk to human health. Researchers have attributed adverse ecological effect effects to the presence of these compounds, particularly EDCs
Iain M McIntyre et al.
Journal of analytical toxicology, 36(3), 177-181 (2012-03-16)
Carisoprodol is a therapeutic and occasionally abused centrally acting muscle relaxant. We compare central blood and liver concentrations of carisoprodol and the metabolite meprobamate to concentrations in peripheral blood in 11 medical examiner cases. Specimens were initially screened for alcohol
Gudrun Høiseth et al.
European journal of clinical pharmacology, 68(11), 1561-1565 (2012-04-25)
Carisoprodol, a frequently used muscle relaxant, can cause potentially fatal intoxications. Conversion to its active metabolite meprobamate is almost solely mediated by cytochrome P450 2C19 (CYP2C19), and mutations in this enzyme could have significant effects on serum concentrations. The objective
Arun Kumar et al.
Regulatory toxicology and pharmacology : RTP, 57(2-3), 146-156 (2010-02-16)
This study presents a step-wise development of a quantitative pharmaceutical risk assessment (QPhRA, hereafter) framework, including Monte Carlo uncertainty analysis for meprobamate, carbamazepine, and phenytoin during (1) accidental exposures of stream water and fish consumption and (2) direct ingestion of
View All Related Papers

Global Trade Item Number

SKUGTIN
M2392-50MG04061833342893
M2392-250MG04061833317839

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