Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

06952

Sigma-Aldrich

Benzocaine

tested according to Ph. Eur.

Synonym(s):

Benzocainum, 4-Aminobenzoic acid ethyl ester, Ethyl 4-aminobenzoate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C9H11NO2
CAS Number:
94-09-7
Molecular Weight:
165.19
Beilstein/REAXYS Number:
638434
EC Number:
202-303-5
MDL number:
MFCD00007892
UNSPSC Code:
12352200
PubChem Substance ID:
329748311

agency

USP/NF
tested according to Ph. Eur.

Quality Level

100

form

crystalline

solubility

alcohol: soluble 1 gm in 5 ml
chloroform: soluble 1 gm in 2 ml
diethyl ether: soluble 1 gm in 4ml
olive oil: soluble 1 gm in 30-50 ml
water: soluble 1 gm in 2500 ml

application(s)

pharmaceutical (small molecule)

SMILES string

CCOC(=O)c1ccc(N)cc1

InChI

1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

Inchi Key

BLFLLBZGZJTVJG-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Benzocaine has been used as animal anesthetic.[1]

Biochem/physiol Actions

Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the nerve membrane, stopping the propagation of the action potential.[2]

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

233.6 °F

flash_point_c

112 °C

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBV1168
BCBT5299
BCBS5889V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Sodium hydroxide BioXtra, ≥98% (acidimetric), pellets (anhydrous)

Sigma-Aldrich

S8045

Sodium hydroxide

Sodium sulfate ACS reagent, ≥99.0%, anhydrous, granular

Sigma-Aldrich

239313

Sodium sulfate

Renin, atrial natriuretic peptide and blood plasma ions in parr and smolts of atlantic salmon salmo salar l. and rainbow trout oncorhynchus mykiss (walbaum) in fresh water and after short-term exposure to sea water.
N. F. Smith
The Journal of Experimental Biology, 63-74 (1991)
Tyrone B Hayes et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(8), 5476-5480 (2002-04-18)
Atrazine is the most commonly used herbicide in the U.S. and probably the world. It can be present at several parts per million in agricultural runoff and can reach 40 parts per billion (ppb) in precipitation. We examined the effects
Sora Lee et al.
The Journal of general physiology, 139(6), 507-516 (2012-05-30)
Recent structural breakthroughs with the voltage-gated sodium channel from Arcobacter butzleri suggest that such bacterial channels may provide a structural platform to advance the understanding of eukaryotic sodium channel gating and pharmacology. We therefore set out to determine whether compounds
L F Rodriguez et al.
The Annals of pharmacotherapy, 28(5), 643-649 (1994-05-01)
To report a case of benzocaine-induced inethemoglobinemia and present a review of the related literature. An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma. The patient became severely cyanotic after induction
Stephan Warnke et al.
Journal of the American Chemical Society, 137(12), 4236-4242 (2015-03-12)
The immediate environment of a molecule can have a profound influence on its properties. Benzocaine, the ethyl ester of para-aminobenzoic acid that finds an application as a local anesthetic, is found to adopt in its protonated form at least two
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service