1.07025

Tetrahydrofuran

≥99.5% (GC), EMPARTA^® ACS reagent

• Synonym(s): THF, Tetramethylene oxide, Oxolane, Butylene oxide, Butylene oxide, Oxolane, Tetramethylene oxide
• Empirical Formula (Hill Notation): C₄H₈O
• CAS Number: 109-99-9
• Molecular Weight: 72.11
• Beilstein/REAXYS Number: 102391
• MDL number: MFCD00005356
• UNSPSC Code: 12191504
• EC Index Number: 203-726-8
• NACRES: NB.21

Properties

• product name: Tetrahydrofuran, for analysis EMPARTA^® ACS
• grade: ACS reagent
• Quality Level: 200
• vapor density: 2.5 (vs air)
• vapor pressure: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• product line: EMPARTA^®
• assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 610 °F
• expl. lim.: 1.8-11.8 %
• impurities: ≤0.01% Peroxide (as H₂O₂); ≤0.05% Water
• evapn. residue: ≤0.03%
• color: clearAPHA: ≤10
• refractive index: n20/D 1.407 (lit.)
• pH: 7-8 (20 °C, 200 g/L in H₂O)
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• transition temp: flash point -21.5 °C
• density: 0.889 g/mL at 25 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI key: WYURNTSHIVDZCO-UHFFFAOYSA-N

Description

General description

EMD Millipore offers EMPARTA grade solvents for routine tasks in analytical laboratories. EMPARTA grade solvents offer fewer test parameters than EMSURE, yet are still of high quality. EMPARTA solvents meet ACS requirements, making them ideal for a wide range of analytical applications.

Application

• Phenylalanine Ammonia Lyase Activity Research: A study investigated the mutase-like activity of phenylalanine ammonia lyase from Anabaena variabilis, demonstrating the utility of buffer concentrate in biochemical assays to stabilize enzyme activity during the research (Weise et al., 2018).



• Studying Amyloid Precursor Protein: A study used buffer concentrate for experiments involving the amyloid precursor protein C-terminal fragment C100, noting its importance in maintaining the stability of protein conformations during interactions with γ-secretase modulators (Botev et al., 2011).

Analysis Note

Purity (GC): ≥ 99.5 %
Identity (IR): conforms
Appearance: clear
Color: ≤ 10 Hazen
Peroxide (as H₂O₂): ≤ 0.01 %
Evaporation residue: ≤ 0.03 %
Water: ≤ 0.05 %
Stabilized with 2,6-Di-tert-butyl-4-methylphenol (BHT).

Legal Information

EMPARTA is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H302,H319,H335,H336,H351
• pcodes: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: -6.2 °F - closed cup
• flash_point_c: -21.2 °C - closed cup