1.06044

Dichloromethane

for liquid chromatography LiChrosolv^®

• Synonym(s): DCM, Methylene chloride, Methylene dichloride, Methylene chloride
• Empirical Formula (Hill Notation): CH₂Cl₂
• CAS Number: 75-09-2
• Molecular Weight: 84.93
• Beilstein/REAXYS Number: 1730800
• MDL number: MFCD00000881
• UNSPSC Code: 12191502
• EC Index Number: 200-838-9
• NACRES: NA.03

Properties

• vapor density: 2.9 (vs air)
• Quality Level: 100
• vapor pressure: 24.45 psi ( 55 °C); 6.83 psi ( 20 °C)
• product line: LiChrosolv^®
• grade: isocratic
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 1223 °F; 605 °C (DIN 51794)
• potency: 1600 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• contains: 2-methyl-2-butene as stabilizer
• expl. lim.: 22 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.01% Water
• evapn. residue: ≤5.0 mg/L
• transmittance: 240 nm, ≥70%; 245 nm, ≥90%; 260 nm, ≥99%
• refractive index: n20/D 1.424 (lit.)
• pH: 7 (20 °C)
• bp: 39.8-40 °C (lit.)
• mp: -95 °C; −95 °C (lit.)
• solubility: 20 g/L
• density: 1.325 g/mL at 25 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

Description

General description

LiChrosolv^® solvents exhibit high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This solution of Ethyl acetate/Ethanol is a greener alternative to dichloromethane for chromatographic purification and thus has been enhanced for Safer Solvents and Auxiliaries. Click here for more information.

Application

Intended for HPLC and UHPLC-MS applications.

Features and Benefits

• suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
• specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
  —ESI/APCI (+) < 2 ppb
  —ESI/APCI (-) < 10 ppb
• lowest impurity profile: for interference-free baselines (test 2)
• microfiltered through 0.2 μm filter (test 3) to provide:
  —a long lifespan to filters and mechanical parts of HPLC systems
  —reduced risk of column clogging
• packed in borosilicate glass bottles for minimum metal ion contaminations
• lowest levels of trace metal impurities for a minimum metal ion adduct formation
  —< 5ppb
• lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 240 nm): ≥ 70 %
Transmission (at 245 nm): ≥ 90 %
Transmission (from 260 nm): ≥ 99 %
Evaporation residue: ≤ 5.0 mg/l
Water: ≤ 0.01 %
The product is stabilized with 2-Methyl-2-buten.
Filtered by 0.2 µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H315,H319,H336,H351
• pcodes: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: does not flash
• flash_point_c: does not flash