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O-902

Supelco

Oxazepam solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C15H11ClN2O2
CAS Number:
604-75-1
Molecular Weight:
286.71
EC Number:
200-659-6
MDL number:
MFCD00057903
UNSPSC Code:
41116107
PubChem Substance ID:
329818934
NACRES:
NA.24

grade

certified reference material

form

liquid

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

OC1N=C(c2ccccc2)c3cc(Cl)ccc3NC1=O

InChI

1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)

InChI key

ADIMAYPTOBDMTL-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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General description

A Certified Spiking Solution® used as a starting material in calibrators and controls for GC/MS or LC/MS testing applications in pain prescription monitoring, clinical toxicology, or forensic analysis. Oxazepam is a benzodiazepine drug used to treat anxiety and insomnia and to control the symptoms of alcohol withdrawal.

Application


  • Oxazepam research solution: Oxazepam is widely used in pharmaceutical research to study its effects and metabolic pathways in the body. Advanced LC-MS/MS methods have been developed to determine oxazepam in biological samples, providing precise data on its pharmacokinetics and pharmacodynamics (Matsuo et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Joel Hellrup et al.
International journal of pharmaceutics, 409(1-2), 96-103 (2011-03-02)
The aim of this study was to explore how pharmaceutical micro-sized filler particles affect the amorphous stability of sucrose in sucrose/filler particle composites produced by freeze-drying. Focus was put on the filler particles' properties crystallinity, hygroscopicity, hydrophobicity, and surface area
M H Lader
Acta psychiatrica Scandinavica. Supplementum, (274)(274), 89-93 (1978-01-01)
The benzodiazepines have been available now for about 15 years but new aspects of their actions are being elucidated all the time. Oxazepam has a short half-life and inactive metabolites and therefore differs from most other benzodiazepines. Some aspects of
Pharmacokinetics in clinical medicine: oxazepam versus other benzodiazepines.
D J Greenblatt et al.
Diseases of the nervous system, 36(5 Pt. 2), 6-13 (1975-05-01)
Maarten Charles J Franck et al.
Patient education and counseling, 83(3), 411-416 (2011-05-31)
We developed a semi-automated leaflet optimizer (ABOP) to improve the readability of Dutch patient information leaflets (PILs). Our aim was to assess whether or not revisions made with ABOP have an effect on traceability and comprehension of PIL information. Two
Olof Beck et al.
Scandinavian journal of clinical and laboratory investigation, 74(8), 681-686 (2014-07-22)
Products for on-site urine drug testing offer the possibility to perform screening for drugs of abuse directly at the point-of-care. This is a well-established routine in emergency and dependency clinics but further evaluation of performance is needed due to inherent
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UHPLC/MS for Drug Detection in Urine

Optimize β-glucuronidase hydrolysis for glucuronide metabolite analysis considering factors like time, temperature, pH, and enzyme concentration.

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