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880126P

Avanti

DSPE-PEG(2000) Maleimide

Avanti Research™ - A Croda Brand 880126P, powder

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt)

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About This Item

CAS Number:
474922-22-0
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (880126P-10mg)
pkg of 1 × 100 mg (880126P-100mg)
pkg of 1 × 25 mg (880126P-25mg)
pkg of 1 × 50 mg (880126P-50mg)
pkg of 1 × 500 mg (880126P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880126P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CCN(C(C=C1)=O)C1=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C

Application

DSPE-PEG(2000) maleimide is suitable for conjugation with photon-sensitive cell penetrating peptides (psCPP) to prepare nanostructured lipid carrier. It is also suitable for non-covalently functionalizing oxidized multi-walled carbon nanotubes (O-MWCNs).

Biochem/physiol Actions

DSPE-PEG(2000) maleimide is used to prepare conjugated polymer nanoparticles. It is suitable for its use in the synthesis of functional conjugates.

Packaging

20 mL Clear Glass Screw Cap Vial (880126P-500mg)
5 mL Amber Glass Screw Cap Vial (880126P-100mg)
5 mL Amber Glass Screw Cap Vial (880126P-10mg)
5 mL Amber Glass Screw Cap Vial (880126P-25mg)
5 mL Amber Glass Screw Cap Vial (880126P-50mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2
Ren J, et al.
Biomaterials, 33(11), 3324-3333 (2012)
Yen Ling Yeow et al.
EMBO molecular medicine, 11(12), e10923-e10923 (2019-11-12)
High extracellular matrix (ECM) content in solid cancers impairs tumour perfusion and thus access of imaging and therapeutic agents. We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds. We target the immune-modulating cytokine
Conjugated Polymers for Biological and Biomedical Applications, 29-29 (2018)
Araz Norouz Dizaji et al.
Journal of biomaterials science. Polymer edition, 31(3), 293-309 (2019-11-26)
This study aims to develop fluorescence labelled polymeric nanoparticle (NP) carrying vancomycin as the targeting agent for in vivo imaging of Methicillin-resistant Staphylococcus aureus bacterial infections in animal models. Maleimide functionalized 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide (polyethylene glycol)-2000] as the main was carrier matrix to
Megan Farell et al.
ACS applied materials & interfaces, 12(11), 12407-12416 (2020-02-23)
Combination therapies utilize multiple mechanisms to target cancer cells to minimize cancer cell survival. Graphene provides an ideal platform for combination therapy due to its photothermal properties and high loading capacity for cancer-fighting molecules. Lipid functionalization of graphene extends its
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