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880126P

Avanti

DSPE-PEG(2000) Maleimide

Avanti Research™ - A Croda Brand 880126P, powder

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt)

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About This Item

CAS Number:
474922-22-0
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (880126P-10mg)
pkg of 1 × 100 mg (880126P-100mg)
pkg of 1 × 25 mg (880126P-25mg)
pkg of 1 × 50 mg (880126P-50mg)
pkg of 1 × 500 mg (880126P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880126P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CCN(C(C=C1)=O)C1=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C

Application

DSPE-PEG(2000) maleimide is suitable for conjugation with photon-sensitive cell penetrating peptides (psCPP) to prepare nanostructured lipid carrier. It is also suitable for non-covalently functionalizing oxidized multi-walled carbon nanotubes (O-MWCNs).

Biochem/physiol Actions

DSPE-PEG(2000) maleimide is used to prepare conjugated polymer nanoparticles. It is suitable for its use in the synthesis of functional conjugates.

Packaging

20 mL Clear Glass Screw Cap Vial (880126P-500mg)
5 mL Amber Glass Screw Cap Vial (880126P-100mg)
5 mL Amber Glass Screw Cap Vial (880126P-10mg)
5 mL Amber Glass Screw Cap Vial (880126P-25mg)
5 mL Amber Glass Screw Cap Vial (880126P-50mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2
Ren J, et al.
Biomaterials, 33(11), 3324-3333 (2012)
Conjugated Polymers for Biological and Biomedical Applications, 29-29 (2018)
Yen Ling Yeow et al.
EMBO molecular medicine, 11(12), e10923-e10923 (2019-11-12)
High extracellular matrix (ECM) content in solid cancers impairs tumour perfusion and thus access of imaging and therapeutic agents. We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds. We target the immune-modulating cytokine
Araz Norouz Dizaji et al.
Journal of biomaterials science. Polymer edition, 31(3), 293-309 (2019-11-26)
This study aims to develop fluorescence labelled polymeric nanoparticle (NP) carrying vancomycin as the targeting agent for in vivo imaging of Methicillin-resistant Staphylococcus aureus bacterial infections in animal models. Maleimide functionalized 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide (polyethylene glycol)-2000] as the main was carrier matrix to
Yang Han et al.
Drug delivery, 27(1), 502-518 (2020-04-02)
Reactive oxygen species (ROS)-induced neuronal mitochondrial dysfunction is a key pathologic factor in sporadic Alzheimer's disease (AD). Neuronal mitochondria have been proposed to be a promising therapeutic target for AD, especially for the failures of phase III clinical trials on
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