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form
liquid
reaction suitability
reaction type: C-C Bond Formation
Application
4-Ethoxycarbonylphenoxytetrafluorobromoethane is a fluoroalkylbromide that is a radical source of the 4-ethoxycarbonylphenoxytetrafluoroethyl moiety. Alternatively, it can also be selectively metallated at the fluorinated carbon with Turbo Grignard reagent at low temperatures resulting in a thermally unstable anion that can act as a nucleophilic fluoroalkylation reagent towards a wide variety of electrophiles, such as aldehydes, ketones or sulfonylimines. The ester group can be transformed to other derivatives, building molecular complexity.
Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)
Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)
Legal Information
Product of CF Plus Chemicals.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Fluoroalkylation toolbox expands with various reagents for late-stage fluoroalkylation in organic synthesis and medicinal chemistry.
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