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68571

Sigma-Aldrich

Aminomethyl ChemMatrix® resin

0.50-0.70 mmol/g loading (amine)

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.22

product line

ChemMatrix®

form

crystals

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

particle size

100-200 mesh

capacity

0.50-0.70 mmol/g loading (amine)

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

Aminomethyl ChemMatrix® resin is a polyethyleneglycol (PEG)-based resin, composed of highly cross-linked primary ether bonds, therefore the resin is chemically and mechanically stable in a broad range of solvents. It has good loading properties when compared to other PEG resins due to its availability in free-flowing powder form. This resin is also more effective than polystyrene resins in the synthesis of hydrophobic or highly structured polypeptides.

Application

Aminomethyl ChemMatrix® resin can be used as efficient support in solid-phase peptide synthesis (SPPS). It is also used as a starting material to synthesize dihydrolipoyl-supported polymer, which is used as an efficient and recyclable reducing agent for the reduction of disulfide compounds.

Legal Information

ChemMatrix is a registered trademark of Matrix Innovation, Inc.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives
Bienvenu C, et al.
Tetrahedron Letters, 51(25), 3309-3311 (2010)
Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins
Gerardo A Acosta, et al.
Journal of Peptide Science, 15(10), 629-633 (2009)
Polyethyleneglycol-based resins as solid supports for the synthesis of difficult or long peptides
Beatriz G, et al.
International Journal of Peptide Research and Therapeutics, 13(1-2), 265-270 (2007)
ChemMatrix for complex peptides and combinatorial chemistry.
Garcia-Ramos Y, et al.
Journal of Peptide Science, 16(12), 675-678 (2010)

Articles

ChemMatrix® Resin for solid phase peptide synthesis

ChemMatrix® is a proprietary, 100% PEG (polyethylene glycol) based resin from PCAS BioMatrix.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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