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659606

Sigma-Aldrich

Poly[(lactide-co-ethylene glycol)-co-ethyloxyphosphate]

Synonym(s):

Poly(LAEG-EOP)

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About This Item

Linear Formula:
[OCCH3CO(OCHCH3CO)xOCH2CH2O(COCHCH3O)yCOCHCH3OPOOCH2CH3]n
MDL number:
MFCD07785556
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

solubility

THF: soluble (readily)
acetonitrile: soluble (readily)
chloroform: soluble (readily)
ethyl acetate: soluble (readily)
hexane: insoluble

General description

The polymer is structurally similar to nucleic and teichoic acids. It undergoes biodegrade through hydrolysis and possibly enzymatic digestion. One of the few classes of polymers for non-viral gene delivery by conjugation of charged groups to the side chain of the phosphate.This biodegradable polymer is soluble in a variety of organic acids.

Physical properties

Biodegradable polymer soluble in a variety of organic acids.[1]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
02527HD

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Zhong Zhao et al.
Advanced drug delivery reviews, 55(4), 483-499 (2003-04-23)
Polymers with repeating phosphoester bonds in the backbone are structurally versatile, and biodegradable through hydrolysis, and possibly enzymatic digestion at the phosphoester linkages under physiological conditions. These biodegradable polyphosphoesters are appealing for biological and pharmaceutical applications because of their potential

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