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534641

Sigma-Aldrich

Amano Lipase PS, from Burkholderia cepacia

≥23,000  U/g, pH 7.0, 50 °C (Optimum pH and temperature)

Synonym(s):

APS-BCL, Pseudomonas cepacia (APS-PCL)

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About This Item

MDL number:
UNSPSC Code:
12352204
NACRES:
NA.22

specific activity

≥23,000  U/g, pH 7.0, 50 °C (Optimum pH and temperature)

Application

Amano Lipase PS is generally used in the enantioselective transesterification and hydrolysis. Applications include:
  • Lipase catalyzed transesterification of prochiral pyrimidine acyclonucleoside.
  • Lipase catalyzed hydrolysis of diacetylated pyrimidine acyclonucleosides.
  • Enantiomer selective acylation of racemic alcohols in continuous-flow bioreactors.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipase-catalyzed enantioselective transesterification of prochiral 1-((1, 3-dihydroxypropan-2-yloxy) methyl)-5, 6, 7, 8-tetrahydroquinazoline-2, 4 (1H, 3H)-dione in ionic liquids.
Kolodziejska, et al.
Chirality, 30(2), 206-214 (2018)
Reverse Stereoselectivity in the Lipase-Catalyzed Hydrolysis of Diacetylated Pyrimidine Acyclonucleosides.
Kolodziejska et al.
ChemCatChem, 8(23), 3644-3649 (2016)
Immobilization of lipase from Burkholderia cepacia into calcium carbonate microcapsule and its use for enzymatic reactions in organic and aqueous media.
Fujiwara M, et al.
Journal of Molecular Catalysis. B, Enzymatic, 109, 94-100 (2014)
Enantiomer selective acylation of racemic alcohols by lipases in continuous-flow bioreactors.
Csajagi C, et al.
Tetrahedron Asymmetry, 19(2), 237-246 (2008)
Dominik Koszelewski et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(43), 10156-10164 (2019-05-29)
A new protocol based on lipase-catalyzed tandem reaction toward α,β-enones/enoesters is presented. For the synthesis of the desired products the tandem process based on enzyme-catalyzed hydrolysis and Knoevenagel reaction starting from enol acetates and aldehyde is developed. The relevant impact

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Efficient epimerization catalyst for enzyme mediated dynamic kinetic resolution (DKR).

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