499498

(R)-(+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution

0.5 M in THF

• Linear Formula: CH₃O₂CCH(CH₃)CH₂ZnBr
• CAS Number: 343338-26-1
• Molecular Weight: 246.42
• MDL number: MFCD06799347
• UNSPSC Code: 12352103
• PubChem Substance ID: 24873285
• NACRES: NA.22

Properties

• concentration: 0.5 M in THF
• density: 0.968 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: O=C([C@H](C[Zn]Br)C)OC
• InChI: 1S/C5H9O2.BrH.Zn/c1-4(2)5(6)7-3;;/h4H,1H2,2-3H3;1H;/q;;+1/p-1/t4-;;/m1../s1
• InChI key: ZYPPBSJLXDMOPY-RZFWHQLPSA-M

Description

Application

(R)-(+)-3-Methoxy-2-methyl-3-oxopropylzinc bromide can be used:

• As an intermediate in one of the key synthetic steps for the preparation of a natural product named (+)-discodermolide.[1]
• As a starting material for the synthesis of (2R,4E)-methyl-2,4-dimethyl-hexanoate, a key intermediate for the preparation of C13-32 fragment of spirangien A.[2]

Legal Information

Product of Rieke Metals, Inc.
Rieke is a registered trademark of Rieke Metals, Inc.

Safety Information

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H261,H302,H319,H335,H336,H351
• pcodes: P202 - P210 - P231 + P232 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3 - Water-react 2
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17 °C - closed cup