Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

477222

Sigma-Aldrich

4-Chloroaniline

purified by sublimation, ≥99%

Synonym(s):

1-Amino-4-chlorobenzene, 4-Chlorophenylamine, p-Chloroaniline

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
$42.18
10 G
$52.63

$42.18

List Price$44.40
Web-Only Promotion

Available to ship onApril 29, 2025Details

Request a Bulk Order
All Photos(2)

Select a Size

Change View
1 G
$42.18
10 G
$52.63

About This Item

Linear Formula:
ClC6H4NH2
CAS Number:
106-47-8
Molecular Weight:
127.57
Beilstein/REAXYS Number:
471359
EC Number:
203-401-0
MDL number:
MFCD00007835
UNSPSC Code:
12352100
PubChem Substance ID:
24871344
NACRES:
NA.22

$42.18

List Price$44.40
Web-Only Promotion

Available to ship onApril 29, 2025Details

Request a Bulk Order

vapor density

4.4 (vs air)

Quality Level

100

vapor pressure

0.15 mmHg ( 25 °C)

assay

≥99%

form

crystals
powder
solid

purified by

sublimation

bp

232 °C (lit.)

mp

67-70 °C (lit.)

functional group

chloro

SMILES string

Nc1ccc(Cl)cc1

InChI

1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI key

QSNSCYSYFYORTR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

4-Chloroaniline (4-ClA) is a chlorinated aromatic amine that is formed as an intermediate during the microbial decomposition of phenylurea and phenylcarbamate.[1] The formation of various oligomers by polymerization of 4-ClA with guaiacol in an aqueous solution containing oxidoreductases has been reported.[2] 4-ClA undergoes decomposition via oxidation by fusarium oxysporum, a soil fungus.[3]

Application

4-Chloroaniline may be used to synthesize:
  • 4-chloronitrosobenzene[4]
  • 2-bromo-4-chloroaniline[5]
  • 2,6-dibromo-4-chloroaniline[5]

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

248.0 °F - closed cup

flash_point_c

120.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000235924
0000223299
0000223299
0000235924
0000104568

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Microbial oxidation of 4-chloroaniline.
D D Kaufman et al.
Journal of agricultural and food chemistry, 21(1), 127-132 (1973-01-01)
M D Corbett et al.
The Biochemical journal, 175(2), 353-360 (1978-11-01)
The incubation of 4-chloroaniline with chloroperoxidase and H2O2 resulted in a rapid formation of 4-chloronitrosobenzene. This enzymic oxidation displayed a pH optimum at 4.4 with a Km of 8.1x10(-4)M and catalytic-centre activity of 312. The initial rate of the reaction
The action of chloride peroxidase on 4-chloroaniline. N-oxidation and ring halogenation.
Corbett MD, et al.
The Biochemical Journal, 187(3), 893-903 (1980)
Oxidative co-oligomerization of guaiacol and 4-chloroaniline.
Simmons KE, et al.
Environmental Science & Technology, 23(1), 115-121 (1989)
Roongnapa Tongarun et al.
Current microbiology, 56(2), 182-188 (2007-11-15)
Bioremediation treatments including natural attenuation (NA), biostimulation (BS), and bioaugmentation (BA) were performed and compared regarding the degradation of 4-chloroaniline (4CA) contaminating two types of agricultural soil collected from Nakornnayok (NN) and Chiangmai (CM) provinces, Thailand. Despite the different soil
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service