Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 26(1), 53-58 (2011-12-20)
The objective of the present study was to investigate if arsenate V exposure results in glutathione efflux from human erythrocytes. The changes in intracellular and extracellular nonprotein sulfhydryl and glutathione levels were determined in arsenate (V) exposed erythrocytes. Presence of
Journal of toxicology and environmental health. Part A, 76(7), 449-457 (2013-04-25)
This study describes a method for measuring the relative oral bioavailability (RBA) of arsenic (As) in soil and other soil-like media using young swine as the animal model. Groups of animals are exposed to site soil or sodium arsenate orally
Over the past two decades, key advancements have been made in understanding the complex pathology that occurs following not only high levels of arsenic exposure (>1 ppm) but also levels previously considered to be low (<100 ppb). Past studies have
Inorganic arsenic is a known human carcinogen, inducing tumors of the skin, urinary bladder and lung. It is metabolized to organic methylated arsenicals. 2,3-Dimercaptopropane-1-sulfonic acid (DMPS), a chelating agent, is capable of reducing pentavalent arsenicals to the trivalent state and
Journal of applied toxicology : JAT, 32(8), 617-626 (2011-12-02)
The embryonic stem cell test (EST) is a validated in vitro embryotoxicity test; however, as the inhibition of cardiac differentiation alone is used as a differentiation endpoint in the EST, it may not be a useful test to screen embryotoxic
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