European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 8(3), 193-201 (1999-06-24)
The effect of the neutron activation factors, i.e., admixture of samarium oxide (Sm2O3) and irradiation time, on the physico-chemical properties of the raw materials and the in vitro dissolution and disintegration of hydrophilic and lipophilic suppositories was investigated. It was
Journal of pharmaceutical sciences, 97(1), 225-236 (2007-08-28)
Treatment of systemic disease with phosphorothioate antisense oligonucleotides (PS ASOs) has been accomplished using local or parenteral routes of administration to date. This report describes, for the first time, the effective oral delivery of a second generation oligonucleotide where significant
International journal of pharmaceutics, 349(1-2), 24-29 (2007-09-18)
The fate of two colon-specific formulations developed in our previous study was investigated using a gamma scintigraphic imaging method. The formulations contained paracetamol and samarium oxide (Sm2O3) and either microcrystalline cellulose (MCC) or hypromellose (HPMC K4M) as diluent and were
Journal of radiation research, 43 Suppl, S67-S69 (2003-06-10)
In order to observe and estimate the dose of ultraviolet (UV) radiation, the thermoluminescence (TL) of sintered CaF2 doped with Tb4O7 and Sm2O3 was studied. A several kind of lanthanides elements are doped in pure CaF2 powder crystals and properties
To develop a robust radiolabeling technique to enable evaluation of difficult to radiolabel gastric retentive formulations using gamma scintigraphy. The use of a successful radiolabel will allow accurate assessment of the gastric residence time of the formulations. The retention of
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