RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Synonyms:
CALDAG-GEFI, CALDAG-GEFII, RASGRP, V, hRasGRP1
Species:
Human RASGRP1 (10125), Mouse Rasgrp1 (19419), Rat Rasgrp1 (29434), sheep RASGRP1 (101105504), domestic guinea pig Rasgrp1 (100735488), Domestic Rabbit RASGRP1 (100359319), Horse RASGRP1 (100071578), cow RASGRP1 (533125), chicken RASGRP1 (423290), domestic cat RASGRP1 (101093110) ...More
UniProtKB ID:
Gene ID:
- Human(10125) Summary: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
- Mouse(19419) RAS guanyl releasing protein 1
- Rat(29434) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- sheep(101105504) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- domestic guinea pig(100735488) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- Domestic Rabbit(100359319) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- Horse(100071578) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- cow(533125) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- chicken(423290) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- domestic cat(101093110) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- dog(478255) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
- naked mole-rat(101699646) RAS guanyl releasing protein 1 (calcium and DAG-regulated)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RASGRP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-RasGRP1 Antibody, clone 10.1, clone 10.1, from mouse,
Species Reactivity
human
Application
western blot
Anti-phospho-RasGRP1(pThr184) antibody, Mouse monoclonal, clone p-RasGRP1-1, purified from hybridoma cell culture,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot