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M6013

Sigma-Aldrich

Medroxyprogesterone

Synonym(s):

17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol

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250 MG
R 2 018,80

R 2 018,80

List PriceR 2 060,00

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250 MG
R 2 018,80

About This Item

Empirical Formula (Hill Notation):
C22H32O3
CAS Number:
Molecular Weight:
344.49
Beilstein:
2510965
EC Number:
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
biological source:
synthetic (organic)
form:
powder
Assay:
≥98% (HPLC)

R 2 018,80

List PriceR 2 060,00

Please contact Customer Service for Availability

Request a Bulk Order

biological source

synthetic (organic)

Quality Level

Assay

≥98% (HPLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O

InChI

1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChI key

FRQMUZJSZHZSGN-HBNHAYAOSA-N

Gene Information

rat ... Ar(24208)

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Caution

Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.

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Description
Pricing

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M F Fung et al.
Obstetrics and gynecology, 78(6), 1033-1038 (1991-12-01)
We conducted a retrospective review of 44 patients with metastatic or recurrent endometrial carcinoma treated with cisplatin, doxorubicin, cyclophosphamide, and medroxyprogesterone acetate. Thirty-six women had metastatic disease; eight had recurrent disease. In the metastatic group, 12 women had positive peritoneal
Clinical significance of differences in bioavailability of medroxyprogesterone acetate preparations.
A D Stockdale et al.
Clinical pharmacokinetics, 16(3), 129-133 (1989-03-01)
Adarsh J Sai et al.
Menopause (New York, N.Y.), 18(10), 1101-1112 (2011-06-30)
The aim of this study was to examine the effect of conjugated equine estrogens alone (ET), conjugated equine estrogens + medroxyprogesterone (EPT), calcitriol alone, calcitriol + EPT/ET, or placebo on serum lipid profile and analyze the interaction with estrogen receptor-α
D R Reilly et al.
Canadian journal of psychiatry. Revue canadienne de psychiatrie, 45(6), 559-563 (2000-09-15)
To propose a protocol for minimizing medical complications associated with the use of cyproterone, medroxyprogesterone, and depot leuprolide to treat paraphilia. Review of the relevant literature. Certain patient populations should not be treated with these medications, and medical complications associated
Kevin D Beck et al.
Neurobiology of learning and memory, 97(1), 148-155 (2011-12-06)
Ovarian hormones modulate acquisition processes involved in classical conditioning. Although progesterone has been indirectly implicated, its role in classical conditioning of the eyeblink response has not been directly investigated. We assessed the effects of daily dosing of progesterone or medroxyprogesterone

Questions

  1. is there is any other solution can be used to dissolve the Medroxyprogesterone and whats the tempreture we need to use for stoarge after dissolving the Medroxyprogesterone

    1 answer
    1. The solubility of this product is tested in chloroform at 50 mg/mL. Solution stability has not been determined, however the acetate form is unstable in solution and should be prepared fresh. The end user would have to validate solution stability of this compound experimentally. The NIH lists the material as being soluble in ethanol, methanol, ether, and acetone. Please see the link below to review this publication:
      https://pubchem.ncbi.nlm.nih.gov/compound/Medroxyprogesterone#section=Color-Form

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