860398P

18:0-d35 Lyso PC

Avanti Research^™ - A Croda Brand 860398P, powder

• Synonym(s): 1-stearoyl-d35-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₂₆H₁₉NO₇PD₃₅
• CAS Number: 327178-92-7
• Molecular Weight: 558.90
• UNSPSC Code: 12352100
• NACRES: NA.25

Properties

• Assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (860398P-10mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860398P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2

Description

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Lysophosphatidylcholine (Lyso PC) is a bioactive proinflammatory phospholipid and a component of oxidized low-density lipoprotein (Ox-LDL). It is produced during various pathological activities.

Biochem/physiol Actions

Lysophosphatidylcholine (Lyso PC) on acylation by yeast protein Ypr140w yields phosphatidylcholine (PC). Lyso PC alters functions in a numerous cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages, and T-cells and leads to the development of atherosclerosis and inflammatory diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860398P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3