47865-U

Nicotinamide (Niacinamide)

analytical standard

• Synonyme(s) : Nicotinamide, Acide nicotinique amide, Acide pyridine-3-carboxylique amide, Vitamine PP, Vitamine B₃
• Formule empirique (notation de Hill): C₆H₆N₂O
• Numéro CAS: 98-92-0
• Poids moléculaire : 122.12
• Numéro Beilstein : 383619
• Numéro CE : 202-713-4
• Numéro MDL: MFCD00006395
• Code UNSPSC : 85151701
• ID de substance PubChem : 329757343
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• CofA (certificat d'analyse): current certificate can be downloaded
• Caractéristiques: standard type water soluble vitamin
• Conditionnement: ampule of 1000 mg
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Pf: 128-131 °C (lit.)
• Application(s): clinical testing
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: NC(=O)c1cccnc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• Clé InChI: DFPAKSUCGFBDDF-UHFFFAOYSA-N
• Informations sur le gène: human ... PARP1(142) , SIRT2(22933)

Description

Description générale

Nicotinamide (Niacinamide), belonging to the class of water-soluble B vitamins, is typically produced from nicotinic acid (vitamin B₃). It is found as a component of food products. It has been suggested for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It also exhibits anti-inflammatory activity.

Application

Nicotinamide (Niacinamide) may be used as a reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Produits recommandés

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Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H319
• Conseils de prudence: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 302.0 °F - closed cup
• Point d'éclair (°C): 150 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves