47864

Acide nicotinique

analytical standard

• Synonyme(s) : Acide 3-picolinique, Acide pyridine-3-carboxylique, Facteur de prévention de la pellagre
• Formule empirique (notation de Hill): C₆H₅NO₂
• Numéro CAS: 59-67-6
• Poids moléculaire : 123.11
• Numéro Beilstein : 109591
• Numéro CE : 200-441-0
• Numéro MDL: MFCD00006391
• Code UNSPSC : 12164500
• ID de substance PubChem : 24871534

Propriétés

• Qualité: analytical standard
• CofA (certificat d'analyse): current certificate can be downloaded
• Caractéristiques: standard type water soluble vitamin
• Conditionnement: ampule of 1000 mg
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Pf: 236-239 °C (lit.)
• Densité: 1.473 g/cm³ at 25 °C
• Application(s): pharmaceutical (small molecule); vitamins, nutraceuticals, and natural products
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: OC(=O)c1cccnc1
• InChI: 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
• Clé InChI: PVNIIMVLHYAWGP-UHFFFAOYSA-N
• Informations sur le gène: human ... CYP1A2(1544) ; rat ... Chrnb2(54239)

Description

Description générale

Nicotinic acid acts as an antilipolytic drug in adipose tissue, and is commonly used for hyperlipoproteinaemia and pellagra.

Nicotinic acid is a water soluble, vitamin belonging to B complex group of vitamins, which can be used as a broad spectrum lipid lowering drug. Its mode of action basically involves the inhibition of the hormone-sensitive triglyceride lipase and thereby, decreasing the lipolysis in adipose tissue.

Application

Nicotinic acid may be used as an analytical reference standard for the quantification of the analyte in tablet dosage forms using reversed-phase high-performance liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produits recommandés

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Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H319
• Conseils de prudence: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 379.4 °F - closed cup
• Point d'éclair (°C): 193 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves