F6300

Flumazenil

>99% (HPLC), solid, benzodiazepine receptor antagonist

• Synonyme(s) : Ro 15-1788, Ro15-1788
• Formule empirique (notation de Hill) : C₁₅H₁₄FN₃O₃
• Numéro CAS: 78755-81-4
• Poids moléculaire : 303.29
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278437
• NACRES: NA.77
• MDL number: MFCD00242764
• Assay: >99% (HPLC)
• Form: solid

Propriétés

• Nom du produit: Flumazenil, >99% (HPLC), solid
• Quality Segment: 100
• assay: >99% (HPLC)
• form: solid
• color: white
• originator: Roche
• storage temp.: 2-8°C
• SMILES string: CCOC(=O)c1ncn-2c1CN(C)C(=O)c3cc(F)ccc-23
• InChI: 1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
• InChI key: OFBIFZUFASYYRE-UHFFFAOYSA-N
• Gene Information: human ... BZRAP1(9256), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879) ; rat ... Gabra2(29706), Gabrg1(140674)

Description

General description

Flumazenil reverses sedative and hypnotic effects of benzodiazepines. It is used to increase acquisition, enhance retention and treat amnesia in mice.

Biochem/physiol Actions

Highly specific benzodiazepine receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)