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Y0000040

Ciclopirox

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone

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About This Item

Formule empirique (notation de Hill):
C12H17NO2
Numéro CAS:
29342-05-0
Poids moléculaire :
207.27
Numéro MDL:
MFCD00599441
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

ciclopirox

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

ON1C(C2CCCCC2)=CC(C)=CC1=O

InChI

1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3

Clé InChI

SCKYRAXSEDYPSA-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ciclopirox EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

C2162700

Ciclopirox olamine, European Pharmacopoeia (EP) Reference Standard

C2162702

Ciclopirox impurity B, European Pharmacopoeia (EP) Reference Standard

C2162701

Ciclopirox impurity A, European Pharmacopoeia (EP) Reference Standard

1134030

Ciclopirox olamine, United States Pharmacopeia (USP) Reference Standard

1134040

Ciclopirox Related Compound B, United States Pharmacopeia (USP) Reference Standard

1134018

Ciclopirox, United States Pharmacopeia (USP) Reference Standard

1134084

Ciclopirox Related Compound C, United States Pharmacopeia (USP) Reference Standard

1134029

Ciclopirox Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR2854

Ciclopirox Related Compound B, certified reference material, pharmaceutical secondary standard

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 + H312 + H332,H319

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Consulter la Bibliothèque de documents

M Bohn et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S57-S69 (2000-10-29)
Ciclopirox is a synthetic hydroxypyridone antifungal agent. In contrast to the azoles, glucuronidation is the main metabolic pathway of ciclopirox; therefore interactions with drugs metabolized via the cytochrome P450 system are unlikely Ciclopirox is also distinct from the common systemic
Ciclopirox: an overview.
A K Gupta
International journal of dermatology, 40(5), 305-310 (2001-09-14)
Aditya K Gupta et al.
International journal of dermatology, 45(1), 66-69 (2006-01-24)
Seborrheic dermatitis is a chronic superficial fungal infection of the skin, particularly affecting sites rich in sebaceous glands. Although the precise etiology of seborrheic dermatitis is uncertain, yeasts of the genus Malassezia are known to play a causative role. Ciclopirox
A K Gupta et al.
Journal of the American Academy of Dermatology, 43(4 Suppl), S96-102 (2000-10-29)
Ciclopirox nail lacquer solution 8% has been shown to be effective in the treatment of dermatophyte onychomycosis of mild to moderate severity Other studies report the effectiveness of ciclopirox nail lacquer in onychomycosis caused by Candida sp and nondermatophyte molds.
Aditya K Gupta et al.
International journal of dermatology, 42 Suppl 1, 3-9 (2003-08-05)
Ciclopirox is a broad-spectrum antifungal agent that also exhibits anti-inflammatory and antibacterial activity. The lotion and cream formulations of ciclopirox are effective in many types of infection, including tinea corporis/cruris, tinea pedis, cutaneous candidiasis, pityriasis (tinea) versicolor, and seborrheic dermatitis.
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