P4722

Pyridoxine hydrochloride

meets USP testing specifications

• Synonyme(s) : PN HCl, Pyridoxol hydrochloride
• Formule empirique (notation de Hill): C₈H₁₁NO₃ · HCl
• Numéro CAS: 58-56-0
• Poids moléculaire : 205.64
• Numéro Beilstein : 3632435
• Numéro CE : 200-386-2
• Numéro MDL: MFCD00012807
• Code UNSPSC : 12352205
• eCl@ss : 34058008
• ID de substance PubChem : 24898493
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Agence: USP/NF; meets USP testing specifications
• Pureté: 98.0-102.0% dry basis
• Forme: powder
• Couleur: white
• Pf: 214-215 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Chaîne SMILES: Cl[H].Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
• Clé InChI: ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Description

Description générale

Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. The food sources of vitamin B₆ include grains, nuts, fruits, vegetables and meat.

Application

Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats. It has also been used as a reference standard to quantify vitamin B₆ in feed and digesta samples using high-performance liquid chromatography(HPLC).

Actions biochimiques/physiologiques

Pyridoxine plays a key role in metabolism both carbohydrates and amino acids. It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels. Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin. Pyridoxine in excess or deficient may lead to neuropathy.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)