ABC840

Anti-BCMA Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, CD269
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: Q02223
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TNFRSF17(608)

Description

Description générale

BCMA (also known as Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, and CD269) is a receptor of BAFF. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

Immunogène

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human BCMA.

Application

Anti-BCMA Antibody is a highly specific rabbit polyclonal antibody, that targets B-cell Maturation Protein & has been tested in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 10 μg/mL from a representative lot detected BCMA in human spleen cells.

Immunofluorescence Analysis: 10 μg/mL from a representative lot detected BCMA in human spleen cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blotting in human spleen, K562, and U937 lysates.

Western Blotting Analysis: 5 μg/mL of this antibody detected BCMA in human spleen, K562, and U937 lysates.

Description de la cible

~27 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable